Price range: $48.00 through $430.00
Name: Semax; ACTH (4-7)
CAS No.: 80714-61-0
Peptide Sequence: H-Met-Glu-His-Phe-Pro-Gly-Pro-OH
Molecular Formula: C37H51N9O10S
Molecular Weight: 813.9
Appearance: White Lyophilized powder
Semax is a synthetic peptide derived from the adrenocorticotropic hormone (ACTH 4–10 fragment).
Originally developed in Russia, Semax is known for its neuroprotective, nootropic, and neurogenic properties. It’s widely studied for enhancing memory, focus, mental clarity, and stress resilience — making it one of the most intriguing peptides in modern neuroscience.
Semax works by modulating brain-derived neurotrophic factor (BDNF) and neurotrophin signaling, which support:
Neurogenesis – growth of new neurons and synaptic connections
Neuroprotection – protecting brain cells from oxidative or ischemic damage
Improved neurotransmitter balance, particularly dopamine and serotonin
Enhanced learning and cognitive processing speed
By increasing BDNF levels, Semax helps the brain adapt to stress, recover from fatigue, and optimize focus and memory.
Semax improves mental clarity, memory retention, and concentration, especially during high cognitive demand or fatigue.
It supports dopaminergic and serotonergic activity, helping stabilize mood, reduce anxiety, and enhance motivation.
Semax shows strong antioxidant and anti-inflammatory effects that may help protect brain cells from damage related to aging or stress.
Clinical and anecdotal reports suggest enhanced information retention and verbal fluency, making it popular among students and professionals.
Semax is used in medical settings to support stroke recovery, cerebral ischemia, and neurological rehabilitation.
Semax is most commonly administered via intranasal spray, ensuring rapid absorption into the brain.
Typical dosage guidelines:
Cognitive support: 300–600 mcg per day (split into 2 doses)
Neurological recovery: 600–900 mcg per day
Cycle length: 5–10 days on, followed by a short break
💡 Always follow medical or research guidelines. Dosages may vary depending on individual goals or study protocols.
Semax is generally well-tolerated and non-toxic, but mild effects may include:
Nasal irritation or dryness
Mild headache or fatigue
Temporary emotional sensitivity
Adverse reactions are rare and usually subside with proper dosage control.
| Feature | Semax | Selank |
|---|---|---|
| Main Effect | Cognitive enhancement, neuroprotection | Anti-anxiety, mood stabilization |
| Mechanism | Increases BDNF and dopamine | Enhances GABA and serotonin balance |
| Use Case | Focus, memory, neuroplasticity | Stress relief, mood balance |
| Administration | Nasal spray | Nasal spray or subcutaneous |
Many users combine Semax + Selank for synergistic cognitive and mood benefits.
Semax may benefit:
Students and professionals under mental strain
Individuals seeking improved cognitive function
Those recovering from neurological injuries
Biohackers and longevity enthusiasts
Multiple studies highlight Semax’s:
Neuroprotective effects in ischemic brain injury
Cognitive improvement in ADHD and cognitive fatigue
Regulation of oxidative stress and neuroplasticity
Its clinical safety record, established in Russia over 20+ years, reinforces its growing global interest.
For research or clinical purposes, only purchase Semax peptide from verified peptide suppliers or compounding pharmacies with purity testing and Certificates of Analysis (COA). Avoid unregulated or non-accredited vendors.
Semax peptide is a powerful nootropic and neuroprotective compound that supports brain health, enhances focus, and promotes mental resilience.
Its safety, versatility, and research-backed benefits make it one of the most promising peptides for cognitive performance and neurological wellness in 2025.
